Presented at the 24th annual meeting of the American Society of Gene and Cell Therapy Regulations
Regulations and Science: Common Sense Approaches to Accelerating Patient Access to Novel Gene and Cell Therapies
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms
Walker et al, Proc Natl Acad Sci U S A, June 1999
In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas.
Reis e Sousa et al, J Exp Med, December 1997
Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice.
Scharton et al, J. Exp. Med. August 1993.