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Adenovirus Type 4 and Type 7 Vaccine, Live Oral
Proper Name
Adenovirus Type 4 & 7 Vaccine, Live Oral
Indication
Active immunization for the prevention of febrile acute respiratory disease caused by Adenovirus Type 4 and Type 7.
Description

Adenovirus Type 4 and Type 7 Vaccine, Live, Oral contains viable, selected strains of human adenovirus Type 4 and human adenovirus Type 7 prepared in human-diploid fibroblast cell cultures (strain WI-38).

Key Regulatory Milestones

09/30/2008 submitted biologics license application (BLA) 125296

07/2004 - Efficacy and safety data in the BLA first submitted

07/16/2009 - Complete Response letter was sent to the applicant

09/13/2010 - submitted a complete response to the Complete Response letter

03/16/2011 - response reset the review clock to a due date

03/16/2011 - PDUFA Goal Date

10/15/2019 - FDA approval date

Advisory Committee

The application was not referred to the Vaccines and Related Biological Products Advisory Committee because the review of information submitted in the Biologics License Application (BLA), including the clinical study design and trial results, did not raise concerns or controversial issues which would have benefited from an advisory committee discussion.

Advanced Facts