Over the last decade structure based protein platforms have been viewed as a potential catalyst for vaccine development. To this end, computer aided vaccine engineering has been applied for the design of recently licensed vaccines for meningitis and shingles prophylaxis and for a Phase 1 vaccine candidate for Respiratory Syncytial Virus (RSV). Recently the team of Walls et al. published results in the journal Cell demonstrating promising immune responses in animals injected with a vaccine candidate generated by computer modeling of the COVID-19 and associated proteins.